Weighing up the benefits of antidepressant drugs

Weighing the risks and benefits of tamoxifen.

Weighing up the cardiovascular benefits of thiazolidinedione therapy: the impact of increased risk of heart failure.

Type 2 diabetes and heart failure commonly occur together and this combination is associated with poor outcomes. The relationship is likely to be multifactorial and also may involve a specific, though ill-defined, diabetic cardiomyopathy. Glucose-lowering therapies may also be associated with an increased risk of heart failure. Data from recent large-scale clinical trials have drawn particular ...

Brazilian daycares: weighing the risks and benefits.

The number of day care centers in Brazil has doubled over the last few years; with this increase has come a rise in the numbers of cases of communicable disease, particularly pneumonia (the main cause of child mortality in Brazil). A study by Dr. Walter V.C. da Fonseca states that a day care child is 5 times more likely to contact pneumonia. However, since the income earned by women in Brazil...

Antidepressant Drugs

Depression is a common mental disorder characterized by sadness, loss of interest or pleasure, feelings of guilt or low self-esteem, sleep or appetite disturbances, fatigue and lack of concentration. The disorder can be either chronic or recurrent, substantially reducing the individual’s capacity to work or study, or perform the activities of daily living [1]. Depression is more common in women...

Weighing up the benefits of work: Behavioral and neural analyses of effort-related decision making

How we decide whether a course of action is worth undertaking is largely unknown. Recently, neuroscientists have been turning to ecological approaches to address this issue, examining how animals evaluate the costs and benefits of different options. We present here evidence from rodents and monkeys that demonstrate the degree to which they take into account work and energetic requirements when ...